个人简介:
李强:博士,教授,博士生导师,现任盐城工学院海洋生物产业研究院院长、盐城工学院水生动物免疫与疾病研究所所长、盐城工学院水生动物医学专业负责人、盐城工学院黄海创新团队带头人。辽宁青年科技奖获得者,江苏省“333”工程第三层次培养对象,盐城市“515”领军人才、辽宁省“百千万人才工程”千人层次、辽宁省农业领域青年科技创新人才、辽宁省高等学校杰出青年学者、辽宁省优秀硕士学位论文指导教师。
研究方向:
比较免疫学、水产动物疾病快速诊断及免疫防控
主持科研项目:
(1)波里氏囊在刺参应答病原菌侵染中的作用及机制研究,国家自然科学基金面上项目,42076112,58万,202101-202412,主持。
(2)波里氏囊在刺参排脏后体腔细胞恢复中的作用研究,国家自然科学基金面上项目,31872544,59万,201901-202212,主持。
(3)仿刺参"化皮病"病原菌侵染机制的研究,国家自然科学青年基金,30800853,19万,200901-201112,主持。
(4)基于微生物调控和免疫防控策略的刺参疾病防控体系示范,国家星火计划重点项目,2015GA650006,60万,201501-201712,主持。
(5)海水养殖动物重要病原库构建及快速检测产品研发,国家海洋局公益性行业专项子任务,201405003-1,318万,201401-201712,主持。
(6)基于胶体金免疫层析技术的异育银鲫鳃出血病快速诊断试纸条研发与应用,江苏省农业科技自主创新专项,CX(18)3028,50万,201808-202108,主持。
(7)养殖刺参病害快速诊断及综合防治技术,辽宁省新型农业社会化服务体系建设示范试点项目,197万,201510-201710,主持。
(8)海蜇种质资源保护及养殖技术开发、集成与示范,辽宁省科技计划项目,2013203001,20万,201301-201512,主持。
(9)刺参腐皮综合征病原快速检测试纸条的研发,辽宁省农业领域青年科技创新人才培养计划项目,2014003,201410-201710,30万,主持。
(10)鮰爱德华菌胶体金快速检测试剂条的研制与应用,辽宁省教育厅高校杰出青年学者计划项目,LJQ2011075,12万,201101-201312,主持。
(11)仿刺参体腔细胞单克隆抗体的研制,辽宁省教育厅一般项目,2008144,2万,200801-201012,主持。
(12)硝基呋喃类代谢物在刺参体内消除规律的研究,辽宁省海洋与渔业厅科技计划项目,2011026,10万,201101-201312,主持。
(13)刺参养殖用优良益生菌高效筛选及微生物制剂创制,辽宁省海洋与渔业厅科技计划项目,201510,10万,201504-201804,主持。
(14)鲫鳃出血病快速免疫学诊断试剂盒的研究与开发,盐城市515领军人才项目,30万,201801-202012,主持。
(15)刺参体腔细胞的再生规律及调控蛋白研究,盐城工学院人才引进项目,30万,2017.4-2019.12,主持。
教科研业绩成果:
(1)Zhang Jialin, Cui Zhengyi, Hu Guangyao, Jiang Xinyu, Wang Jia, Qiao Guo, Li Qiang*. Transcriptome analysis provides insights into the antiviral response in the spleen of gibel carp (Carassius auratus gibelio) after poly I: C treatment. Fish & Shellfish Immunology 2020,102:13-19 .(SCI 一区,通讯作者)
(2)Zhang Mingming, Wang Jiawei, Sun Qirui, Zhang Hu, Chen Peng, Li Qiang*, Wang Yinan, Qiao Guo*.Immune response of molluscs Onchidium struma to extremely low-frequency electromagnetic fields (ELF-EMF, 50 Hz) exposure based on immune-related enzyme activity and De novo transcriptome analysis. Fish & Shellfish Immunology 2020, 98: 574-584.(SCI 一区,共同通讯)
(3)Ren Yuan#, Zhang Jialin#, Wang Yinan, Chen jing, Liang Chunlei, Li Ruijun, Li Qiang*. Non-specific immune factors differences in coelomic fluid from polian vesicle and coelom of Apostichopus japonicus, and their early response after evisceration. Fish & Shellfish Immunology 2020, 98:160-166.(SCI 一区,通讯作者)
(4)Qiao Guo#, Chen Peng#, Sun Qirui, Zhang Mingming, Zhang Jialin, Li Zhen, Li Qiang*. poly-β-hydroxybutyrate (PHB) in bioflflocs alters intestinal microbial community structure, immune-related gene expression and early Cyprinid herpesvirus 2 replication in gibel carp (Carassius auratus gibelio). Fish & Shellfish Immunology 2020, 97: 72-82.(SCI 一区,通讯作者)
(5)Shi Weibo#, Zhang Jialin#, Wang Yinan, Ji Jinlin, Guo Liyuan, Ren Yuan, Qiao Guo, Wang QingKui, Li Qiang*. Transcriptome analysis of Apostichopus japonicus polian vesicles in response to evisceration. Fish & Shellfish Immunology 2020, 97:108-113.(SCI 一区,通讯作者)
(6)Zhang Mingming#, He Pei#,Qiao Guo, Wang Jiawei, Huang Jintian, Yuan Xiutang, Li Qiang*. Distribution, sources, and risk assessment of polycyclic aromatic hydrocarbons (PAHs) in surface sediments of the Subei Shoal, China. Marine Pollution Bulletin, 2019, 149:110640.(SCI 二区,通讯作者)
(7)Qiao Guo, Sun Qirui, Zhang Mingming, Xu Chen, Lv Tingli, Qi Zhitao, Yang Wenping, Li Qiang* Antioxidant system of soiny mullet (Liza haematocheila) is responsive to dietary poly-β-hydroxybutyrate (PHB) supplementation based on immune-related enzyme activity and de novo transcriptome analysis. Fish & Shellfish Immunology, 2019, 95:314-327. (SCI 一区,通讯作者)
(8)Qiao Guo#, Xu Chen#, Sun Qirui, Xu Dehai, Zhang Mingming, Chen Peng, Li Qiang*. Effects of dietary poly-β-hydroxybutyrate supplementation on the growth, immune response and intestinal microbiota of soiny mullet (Liza haematocheila). Fish & Shellfish Immunology, 2019, 91:251-263(SCI 一区,通讯作者)
(9)Zhang Mingming#, He Pei#, Qiao Guo, Huang Jintian, Yuan Xiutang, Li Qiang*. Heavy metal contamination assessment of surface sediments of the Subei Shoal,China: Spatial distribution, source apportionment and ecological risk. Chemosphere, 2019,223:211-222. (SCI 二区,通讯作者)
(10)Li Qiang#, Ren Yuan#, Luan Linlin, Zhang Jialin, Qiao Guo, Wang Yinan, Ye Shigen, Li Ruijun. Localization and characterization of hematopoietic tissues in adult sea cucumber, Apostichopus japonicus. Fish & Shellfish Immunology, 2019, 84:1-7. (SCI 一区)
(11)Li Qiang, Qiao Guo, Wang Li, Zhang Jipeng, Li Ruijun, Ni Ping, Guo Yi, Ye Shigen. Studies on Bacterial Diversity and Vibrio harveyi Distribution Associated with Diseased fugu (Takifugu rubripes) in Northeastern China. Pakistan Journal of Zoology, 2019, 51(1):67-77. (SCI 四区)
(12)Zhang Mingming, Xu Yang, Kim Sukyoung, Wu Qiuxian, Qi Zhitao, Pang Zhenguo, Qiao Guo*, Li Qiang*. Molecular Characterization, Structure and Expression Analysis of A Ras-related Nuclear (Ran) Gene in Pacific White Shrimp, Litopenaeus vannamei. International Journal of Agriculture and Biology, 2019, 21(1): 11-18(SCI 四区,共同通讯)
(13)Zhang Mingming, He Pei, Liu Pu, Shen Yonglong, Qiao Guo*, Li Qiang*, Huang Jintian. Acute toxicity of heavy metals to Onchidium struma under different salinities. International Journal of Agriculture and Biology, 2019, 21:307-313(SCI 四区,共同通讯)
(14)Li Qiang#, Ren Yuan#, Liang Chunlei, Qiao Guo, Wang Yinan, Ye Shigen, Li Ruijun. Regeneration of coelomocytes after evisceration in the sea cucumber, Apostichopus japonicus. Fish & Shellfish Immunology, 2018, 76:266-271. (SCI 一区)
(15)Wang Yinan, Meng Shaodong, Zhang Jialin, Ding Jun, Li Qiang*. Production, characterization and application of monoclonal antibodies to the coelomocytes of sea urchin Strongylocentrotus Intermedius. Fish & Shellfish Immunology, 2018, 75:301-307 (SCI 一区,通讯作者)
(16)Qiao G, Zhang Mingming, Li Ye, Xu Chen, Xu Dehai, Zhao Zhigang, Zhang Jialin, Li Qiang*. Biofloc technology (BFT): An alternative aquaculture system for prevention of Cyprinid herpesvirus 2 infection in gibel carp (Carassius auratus gibelio). Fish & Shellfish Immunology, 2018, 83:140-147. (SCI 一区,通讯作者)
(17)Ye Shigen, Xie Mingxu, Li Ruijun, Zhang Chao, Yang Jing, Bai Lu, Li Qiang* Screening and Characterization of Acid-Producing Bacteria from High pH Saline-alkali Areas. International Journal of Agriculture and Biology, 2018, 20(7):1682-1690 (SCI 四区,通讯作者)
(18)Ye Shigen, Liu Meiru,Wang Li, Li Ruijun, Li Qiang*. Composition and Diversity of Intestinal Microbiota of Sea Cucumber Apostichopus japonicus from Different Habitats.. International Journal of Agriculture and Biology, 2018,20(8):1868-1872. (SCI 四区,通讯作者)
(19)Li Ruijun, Gao Yanqi, Hou Yulin, Ye Shigen, Wang Lianshun, Sun Jingxian, Li Qiang*. Mitochondrial genome sequencing and analysis of scuticociliates Uronema marinum isolated from Takifugu rubripes. Mitochondrial DNA Part B, 2018, 3:2, 736-737. (SCI 四区,通讯作者)
(20)Li Ruijun, Zhang Xianyu, Yang Chuan, Ye Shigen, Li Hua, Li Qiang*.Development of a Colloidal Gold-Based Immunochromatographic Assay for the Rapid Detection of Edwardsiella Ictaluri. Journal of Nanoscience and Nanotechnology, 2018, 18(6): 3800-3805. (SCI 三区,通讯作者)
(21)Zhang Mingming, Li Ye, Xu Dehai, Qiao Guo*, Zhang Jialin, Qi Zhitao, Li Qiang*.. Effect of different water biofloc contents on the growth and immune response of gibel carp cultured in zero water exchange and no feed addition system. Aquaculture research, 2018,49:1547-1556(SCI 三区,共同通讯)
(22)Li Qiang, Wang Youjuan, Zhang Mingming,Li Ruijun,Ye Shigen, Li Hua. .Production and characterization of monoclonal antibodies against recombinant ORF 049L of rock bream iridovirus. Process Biochemistry, 2016,51(12):2238-2242. (SCI 三区,通讯作者)
(23)Li Qiang, Qi Rui-rong, Wang Yi-nan, Li Hua* Ontogenesis of coelomocytes in sea cucumber (Apostichopus japonicus) studied with probes of monoclonal antibody. Fish & Shellfish Immunology, 2014, 41(2):260-263. (SCI 一区)
(24)Li Qiang, Qi Rui-rong, Wang Yi-nan, Ye Shi-gen, Qiao Guo, Li Hua*. Comparison of cells free in coelomic and water-vascular system of sea cucumber Apostichopus japonicus. Fish & Shellfish Immunology, 2013, 35:1654-1657. (SCI 一区)
(25)Li Qiang, Jing Hong-li, Li Hua*, Wang Yi-nan, Xu De-hai. Characterization and application of monoclonal antibodies against Shewanella marisflavi, a novel pathogen of Apostichopus japonicus. Chinese journal of Oceanology and Limnology, 2011, 29(5):973-980. (SCI 四区)
(26)Li Qiang, Li Ying, Li Hua, Wang Yinan, Xu De-hai. Production characterization and application of monoclonal antibody to spherulocytes A subpopulation of coelomocytes of Apostichopus japonicus. Fish & Shellfish Immunology, 2010, 29:832-838. (SCI 一区)
(27)Li Qiang, Zhan Wen-bin, Xing Jing, Sheng Xiu-zhen. Production, characterisation and applicability of monoclonal antibodies to immunoglobulin of Japanese flounder (Paralichthys olivaceus). Fish & Shellfish Immunology, 2007, 23:982-990. (SCI 一区)
(28)李强,杨川,叶仕根,黎睿君,李华.胶体金层析试纸条金标垫的处理方法.授权日2018.4.17,授权号:ZL 201610306907.X
(29)李强,张显昱,李华,叶仕根,黄华.鮰爱德华菌胶体金免疫层析试纸条及制备方法.授权日:2015.2.18 授权号:ZL201310218944.1
(30)李强,李华,刘志强,叶仕根,景宏丽.黄海希瓦氏菌胶体金免疫层析试纸条及制备方法.授权日:2015.4.15.授权号:ZL 201310218943.7
(31)李强,王博雅,黎睿君,叶仕根. 灿烂弧菌胶体金免疫层析试纸条及制备方法.授权日:2019.4.2.授权号:ZL 201710795942.7
(32)刺参疾病的发生机制及无公害防控技术研究与应用,辽宁省科技进步二等奖,第二完成人,2014年11月,证书号2014J-2-15-02。
(33)刺参疾病无公害防控技术的研究与应用,大连市科技进步一等奖,第二完成人,2014年11月,证书号2013-J-01-02
(34)刺参疾病的发生机制及无公害防控技术研究与示范,国家海洋局海洋科学技术二等奖,第二完成人,2014年5月,证书号HKJ2013-G-2-B32-02