个人简介:
葛小东,男,博士,讲师,盐城工学院海洋与生物工程学院专职教师。
研究方向:
针对2型糖尿病,利用多组学技术,在分子、细胞及整体动物水平上,开展黄酮类化合物的结构修饰和药理学研究,以及宿主与肠道菌群的关联性作用机制分析。
发表论文:
1. Xiaodong Ge, Chao Zhao, Bin Liu. Amelioration of type 2 diabetes by the novel 6, 8-guanidyl luteolin quinone-chromium coordination via biochemical mechanisms and gut microbiota interaction. Journal of Advanced Research, 2022, DOI: 10.1016/j.jare.2022.06.003.
2. Xiaodong Ge, Ying Huang, Bin Liu. 6, 8-(1, 3-diaminoguanidine) luteolin and its Cr complex show hypoglycemic activities and alter intestinal microbiota composition in type 2 diabetes mice. Food&Function, 2022, 13(6): 3572-3589.
3. Xiaodong Ge, Feng Zeng, Bin Liu. Luteolin cooperated with metformin hydrochloride alleviates lipid metabolism disorders and optimizes intestinal flora compositions of high-fat diet mice. Food&Function, 2020, 11(11): 10033-10046.
授权专利:
1. 刘斌, 葛小东, 童爱均, 等. 一种5',8-二(二甲基双胍基)木犀草素-铬(III)络合物. 授权公告号:CN 110437284B.
2. 刘斌, 葛小东, 曾峰, 等. 一种胍基木犀草素-铬(III)络合物及其制备方法. 授权公告号: CN 110305165B.
3. 许伟, 葛小东, 邵荣, 等. 一种乙酰蓖麻油酸甲酯的制备方法. 授权公告号:CN103992223B.